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NPM1 antibody (AA 1-294)
This anti-NPM1 antibody is a Mouse Monoclonal antibody detecting NPM1 in WB, ELISA, IF and IHC (p). Suitable for Human. This Primary Antibody has been cited in 1 publication.
Quick Overview for NPM1 antibody (AA 1-294) (ABIN562035)
Target
See all NPM1 Antibodies
NPM1
(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
Reactivity
All reactivities for NPM1 antibodies
Human
Host
All hosts for NPM1 antibodies
Mouse
Clonality
All clonalities for NPM1 antibodies
Monoclonal
Conjugate
All conjugates for NPM1 antibodies
This NPM1 antibody is un-conjugated
Application
All applications for NPM1 antibodies
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Clone
3B2
Product Details anti-NPM1 Antibody
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Binding Specificity
All epitopes for NPM1 antibodies
AA 1-294
Purpose
Mouse monoclonal antibody raised against a full length recombinant NPM1.
Sequence
MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE EDAESEDEEE EDVKLLSISG KRSAPGGGSK VPQKKVKLAA DEDDDDDDEE DDDEDDDDDD FDDEEAEEKA PVKKSIRDTP AKNAQKSNQN GKDSKPSSTP RSKGQESFKK QEKTPKTPKG PSSVEDIKAK MQASIEKGGS LPKVEAKFIN YVKNCFRMTD QEAIQDLWQW RKSL
Cross-Reactivity
Human
Characteristics
Antibody Reactive Against Recombinant Protein.
Immunogen
NPM1 (AAH02398.1, 1 a.a. ~ 294 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotype
IgG1
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
References for anti-NPM1 antibody (ABIN562035)
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El Hajj, Dassouki, Berthier, Raffoux, Ades, Legrand, Hleihel, Sahin, Tawil, Salameh, Zibara, Darwiche, Mohty, Dombret, Fenaux, de Thé, Bazarbachi : "Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells. " in: Blood , Vol. 125 , Issue 22 , pp. 3447-54 , (2015 ) (PubMed ).
Target Details for NPM1
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Target
NPM1
(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
Alternative Name
NPM1
Background
Full Gene Name: nucleophosmin (nucleolar phosphoprotein B23, numatrin) Synonyms: B23,MGC104254,NPM
Gene ID
4869
Pathways
Ribonucleoprotein Complex Subunit Organization , Ribosome Assembly
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