CD73 antibody (AA 28-264)

Catalog No. ABIN562052

Product Details anti-CD73 Antibody

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Binding Specificity: AA 28-264

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD73 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a full length recombinant NT5E.

Sequence: ELTILHTNDV HSRLEQTSED SSKCVNASRC MGGVARLFTK VQQIRRAEPN VLLLDAGDQY QGTIWFTVYK GAEVAHFMNA LRYDAMALGN HEFDNGVEGL IEPLLKEAKF PILSANIKAK GPLASQISGL YLPYKVLPVG DEVVGIVGYT SKETPFLSNP GTNLVFEDEI TALQPEVDKL KTLNVNKIIA LGHSGSEMDK LIAQKVRGVD VVVGGHSNTF LYTGNCFKRI AWARMSR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: NT5E (AAH15940.1, 28 a.a. ~ 264 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 4C4-2B5

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CD73 antibody (ABIN562052)

Delcourt, Quevedo, Nonne, Fons, OBrien, Loyaux, Diez, Autelitano, Guillemot, Ferrara, Muriana, Callol, Hérault, Herbert, Favre, Bono: "Targeted identification of sialoglycoproteins in hypoxic endothelial cells and validation in zebrafish reveal roles for proteins in angiogenesis." in: The Journal of biological chemistry, Vol. 290, Issue 6, pp. 3405-17, (2015) (PubMed).

Garcia-Esparcia, Hernández-Ortega, Ansoleaga, Carmona, Ferrer: "Purine metabolism gene deregulation in Parkinson's disease." in: Neuropathology and applied neurobiology, (2015) (PubMed).

Crane, Shulgina, Naeher: "Ecto-5'-nucleotidase and intestinal ion secretion by enteropathogenic Escherichia coli." in: Purinergic signalling, Vol. 3, Issue 3, pp. 233-46, (2008) (PubMed).

Target Details for CD73

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Alternative Name: NT5E (NT5E Products)

Synonyms: CALJA antibody, CD73 antibody, E5NT antibody, NT antibody, NT5 antibody, NTE antibody, eN antibody, eNT antibody, zgc:63784 antibody, NT5E antibody, MGC114869 antibody, PSPTO2277 antibody, 2210401F01Rik antibody, AI447961 antibody, Nt5 antibody, 5'-nucleotidase ecto antibody, 5'-nucleotidase, ecto (CD73) antibody, 5'-nucleotidase antibody, 5' nucleotidase, ecto antibody, NT5E antibody, nt5e antibody, nt5e.S antibody, PSPTO_2277 antibody, CBU_1233 antibody, MCA1322 antibody, Nt5e antibody

Background: Full Gene Name: 5'-nucleotidase, ecto (CD73)
Synonyms: CD73,E5NT,NT,NT5,NTE,eN,eNT

Gene ID: 4907

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process