PHF1 antibody (AA 2-100)

Catalog No. ABIN562208

The Mouse Monoclonal anti-PHF1 antibody has been validated for WB and ELISA. It is suitable to detect PHF1 in samples from Human. There are 3+ publications available.

Quick Overview for PHF1 antibody (AA 2-100) (ABIN562208)

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PHF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2D3

Product Details anti-PHF1 Antibody

Binding Specificity: AA 2-100

Purpose: Mouse monoclonal antibody raised against a partial recombinant PHF1.

Sequence: AQPPRLSRSG ASSLWDPASP APTSGPRPRL WEGQDVLARW TDGLLYLGTI KKVDSAREVC LVQFEDDSQF LVLWKDISPA ALPGEELLCC VCRSETVVP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PHF1 (NP_077084, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PHF1 antibody (ABIN562208)

Wang, Cheng, Qin, Jia: "Val97Leu mutant presenilin-1 induces tau hyperphosphorylation and spatial memory deficit in mice and the underlying mechanisms." in: Journal of neurochemistry, Vol. 121, Issue 1, pp. 135-45, (2012) (PubMed).

Hong, Jiang, Lan, Nakajima, Kanno, Koseki, Yasui: "A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell." in: Nucleic acids research, Vol. 36, Issue 9, pp. 2939-47, (2008) (PubMed).

Lazarov, Morfini, Pigino, Gadadhar, Chen, Robinson, Ho, Brady, Sisodia: "Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 26, pp. 7011-20, (2007) (PubMed).

Target Details for PHF1

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Alternative Name: PHF1

Background: Full Gene Name: PHD finger protein 1
Synonyms: MTF2L2,PCL1,PHF2

Gene ID: 5252

NCBI Accession: NM_024165