PITX2 antibody (AA 1-324)

Catalog No. ABIN562251

Cited in 2+ publications. The Mouse Monoclonal anti-PITX2 antibody (Clone 2G6) (ABIN562251) specifically detects PITX2 in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for PITX2 antibody (AA 1-324) (ABIN562251)

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PITX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2G6

Product Details anti-PITX2 Antibody

Binding Specificity: AA 1-324

Purpose: Mouse monoclonal antibody raised against a full length recombinant PITX2.

Sequence: MNCMKGPLHL EHRAAGTKLS AVSSSSCHHP QPLAMASVLA PGQPRSLDSS KHRLEVHTIS DTSSPEAAEK DKSQQGKNED VGAEDPSKKK RQRRQRTHFT SQQLQELEAT FQRNRYPDMS TREEIAVWTN LTEARVRVWF KNRRAKWRKR ERNQQAELCK NGFGPQFNGL MQPYDDMYPG YSYNNWAAKG LTSASLSTKS FPFFNSMNVN PLSSQSMFSP PNSISSMSMS SSMVPSAVTG VPGSSLNSLN NLNNLSSPSL NSAVPTPACP YAPPTPPYVY RDTCNSSLAS LRLKAKQHSS FGYASVQNPA SNLSACQYAV DRPV

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PITX2 (AAH13998, 1 a.a. ~ 324 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PITX2 antibody (ABIN562251)

Strungaru, Footz, Liu, Berry, Belleau, Semina, Raymond, Walter: "PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3." in: Investigative ophthalmology & visual science, Vol. 52, Issue 10, pp. 7625-33, (2011) (PubMed).

Acharya, Lingenfelter, Huang, Gage, Walter: "Human PRKC apoptosis WT1 regulator is a novel PITX2-interacting protein that regulates PITX2 transcriptional activity in ocular cells." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34829-38, (2009) (PubMed).

Target Details for PITX2

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Alternative Name: PITX2

Background: Full Gene Name: paired-like homeodomain 2
Synonyms: ARP1,Brx1,IDG2,IGDS,IGDS2,IHG2,IRID2,MGC111022,MGC20144,Otlx2,PTX2,RGS,RIEG,RIEG1,RS

Gene ID: 5308

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development