PKM2 antibody (AA 1-531)

Catalog No. ABIN562254

This anti-PKM2 antibody is a Mouse Polyclonal antibody detecting PKM2 in WB and ELISA. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for PKM2 antibody (AA 1-531) (ABIN562254)

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PKM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PKM2 Antibody

Binding Specificity: AA 1-531

Purpose: Mouse polyclonal antibody raised against a full-length recombinant PKM2.

Sequence: MSKPHSEAGT AFIQTQQLHA AMADTFLEHM CRLDIDSPPI TARNTGIICT IGPASRSVET LKEMIKSGMN VARLNFSHGT HEYHAETIKN VRTATESFAS DPILYRPVAV ALDTKGPEIR TGLIKGSGTA EVELKKGATL KITLDNAYME KCDENILWLD YKNICKVVEV GSKIYVDDGL ISLQVKQKGA DFLVTEVENG GSLGSKKGVN LPGAAVDLPA VSEKDIQDLK FGVEQDVDMV FASFIRKASD VHEVRKVLGE KGKNIKIISK IENHEGVRRF DEILEASDGI MVARGDLGIE IPAEKVFLAQ KMMIGRCNRA GKPVICATQM LESMIKKPRP TRAEGSDVAN AVLDGADCIM LSGETAKGDY PLEAVRMQHL IAREAEAAIY HLQLFEELRR LAPITSDPTE ATAVGAVEAS FKCCSGAIIV LTKSGRSAHQ VARYRPRAPI IAVTRNPQTA RQAHLYRGIF PVLCKDPVQE AWAEDVDLRV NFAMNVGKAR GFFKKGDVVI VLTGWRPGSG FTNTMRVVPV P

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PKM2 (AAH07640.1, 1 a.a. ~ 531 a.a) full-length recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PKM2 antibody (ABIN562254)

Iglesias-Guimarais, Gil-Guiñon, Gabernet, García-Belinchón, Sánchez-Osuna, Casanelles, Comella, Yuste: "Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease." in: The Journal of biological chemistry, Vol. 287, Issue 10, pp. 7766-79, (2012) (PubMed).

Target Details for PKM2

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Alternative Name: PKM2

Background: Full Gene Name: pyruvate kinase, muscle
Synonyms: CTHBP,MGC3932,OIP3,PK3,PKM,TCB,THBP1

Gene ID: 5315

Pathways: Warburg Effect