LGMN antibody (AA 1-433)

Catalog No. ABIN562455

This anti-LGMN antibody is a Mouse Monoclonal antibody detecting LGMN in ELISA. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for LGMN antibody (AA 1-433) (ABIN562455)

Target: LGMN (Legumain (LGMN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LGMN antibody is un-conjugated

Application: ELISA

Clone: M1

Product Details anti-LGMN Antibody

Binding Specificity: AA 1-433

Purpose: Mouse monoclonal antibody raised against a partial recombinant LGMN.

Sequence: MVWKVAVFLS VALGIGAIPI DDPEDGGKHW VVIVAGSNGW YNYRHQADAC HAYQIIHRNG IPDEQIVVMM YDDIAYSEDN PTPGIVINRP NGTDVYQGVP KDYTGEDVTP QNFLAVLRGD AEAVKGIGSG KVLKSGPQDH VFIYFTDHGS TGILVFPNED LHVKDLNETI HYMYKHKMYR KMVFYIEACE SGSMMNHLPD NINVYATTAA NPRESSYACY YDEKRSTYLG DWYSVNWMED SDVEDLTKET LHKQYHLVKS HTNTSHVMQY GNKTISTMKV MQFQGMKRKA SSPVPLPPVT HLDLTPSPDV PLTIMKRKLM NTNDLEESRQ LTEEIQRHLD ARHLIEKSVR KIVSLLAASE AEVEQLLSER APLTGHSCYP EALLHFRTHC FNWHSPTYEY ALRHLYVLVN LCEKPYPLHR IKLSMDHVCL GHY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: LGMN (AAH03061.1, 1 a.a. ~ 433 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-LGMN antibody (ABIN562455)

Liu, Bajjuri, Liu, Sinha: "Targeting cell surface alpha(v)beta(3) integrin increases therapeutic efficacies of a legumain protease-activated auristatin prodrug." in: Molecular pharmaceutics, Vol. 9, Issue 1, pp. 168-75, (2012) (PubMed).

Target Details for LGMN

Target: LGMN (Legumain (LGMN))

Alternative Name: LGMN

Background: Full Gene Name: legumain
Synonyms: AEP,LGMN1,PRSC1

Gene ID: 5641

Pathways: Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades