Radixin antibody (AA 1-583)

Catalog No. ABIN562623

Cited in 4+ publications. The Mouse Monoclonal anti-Radixin antibody (Clone 1D9) (ABIN562623) specifically detects Radixin in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for Radixin antibody (AA 1-583) (ABIN562623)

Target: Radixin (RDX)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Radixin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 1D9

Product Details anti-Radixin Antibody

Binding Specificity: AA 1-583

Purpose: Mouse monoclonal antibody raised against a full length recombinant RDX.

Sequence: MPKPINVRVT TMDAELEFAI QPNTTGKQLF DQVVKTVGLR EVWFFGLQYV DSKGYSTWLK LNKKVTQQDV KKENPLQFKF RAKFFPEDVS EELIQEITQR LFFLQVKEAI LNDEIYCPPE TAVLLASYAV QAKYGDYNKE IHKPGYLAND RLLPQRVLEQ HKLTKEQWEE RIQNWHEEHR GMLREDSMME YLKIAQDLEM YGVNYFEIKN KKGTELWLGV DALGLNIYEH DDKLTPKIGF PWSEIRNISF NDKKFVIKPI DKKAPDFVFY APRLRINKRI LALCMGNHEL YMRRRKPDTI EVQQMKAQAR EEKHQKQLER AQLENEKEKR EIAEKEKERI EREKEELMER LKQIEEQTIK AQKELEEQTR KALELDQERK RAKEEAERLE KERRAAEEAK SAIAKQAADQ MKNQEQLAAE LAEFTAKIAL LEEAKKKKEE EATEWQHKAF AAQEDLEKTK EELKTVMSAP PPPPPPPVIP PTENEHDEHD ENNAEASAEL SNEGVMNHRS EEERVTETQK NERVKKQLQA LSSELAQARD ETKKTQNDVL HAENVKAGRD KYKTLRQIRQ GNTKQRIDEF EAM

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RDX (AAH47109, 1 a.a. ~ 583 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Radixin antibody (ABIN562623)

Shin, Krey, Hassan, Metlagel, Tauscher, Pagana, Sherman, Jeffery, Spinelli, Zhao, Wilmarth, Choi, David, Auer, Barr-Gillespie: "Molecular architecture of the chick vestibular hair bundle." in: Nature neuroscience, Vol. 16, Issue 3, pp. 365-74, (2013) (PubMed).

Persson, Osman, Bolouri, Mallard, Kuhn: "Radixin expression in microglia after cortical stroke lesion." in: Glia, Vol. 61, Issue 5, pp. 790-9, (2013) (PubMed).

Persson, Lindberg, Kuhn: "Radixin inhibition decreases adult neural progenitor cell migration and proliferation in vitro and in vivo." in: Frontiers in cellular neuroscience, Vol. 7, pp. 161, (2013) (PubMed).

Zhao, Williams, Shin, Brügger, Gillespie: "Large membrane domains in hair bundles specify spatially constricted radixin activation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 13, pp. 4600-9, (2012) (PubMed).

Target Details for Radixin

Target: Radixin (RDX)

Alternative Name: RDX

Background: Full Gene Name: radixin
Synonyms: DFNB24

Gene ID: 5962

Pathways: Regulation of Actin Filament Polymerization, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome