RNF2 antibody (AA 192-290)

Catalog No. ABIN562662

This anti-RNF2 antibody is a Mouse Monoclonal antibody detecting RNF2 in WB, ELISA and RNAi. Suitable for Human. This Primary Antibody has been cited in 3+ publications.

Quick Overview for RNF2 antibody (AA 192-290) (ABIN562662)

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RNF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, RNA Interference (RNAi)

Clone: 6C2

Product Details anti-RNF2 Antibody

Binding Specificity: AA 192-290

Purpose: Mouse monoclonal antibody raised against a partial recombinant RNF2.

Sequence: PSNKRTKTSD DSGLELDNNN AAMAIDPVMD GASEIELVFR PHPTLMEKDD SAQTRYIKTS GNATVDHLSK YLAVRLALEE LRSKGESNQM NLDTASEKQ

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RNF2 (NP_009143, 192 a.a. ~ 290 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RNF2 antibody (ABIN562662)

Yasunaga, Ohtsubo, Ohno, Saeki, Kurogi, Tanaka-Okamoto, Ishizaki, Shirai, Mihara, Brock, Miyoshi, Takihara: "Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4." in: Molecular and cellular biology, Vol. 33, Issue 4, pp. 644-60, (2013) (PubMed).

Rugg-Gunn, Cox, Ralston, Rossant: "Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 24, pp. 10783-90, (2010) (PubMed).

Ohtsubo, Yasunaga, Ohno, Tsumura, Okada, Ishikawa, Shirao, Kikuchi, Nishitani, Kobayashi, Takihara: "Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 30, pp. 10396-401, (2008) (PubMed).

Target Details for RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Alternative Name: RNF2

Background: Full Gene Name: ring finger protein 2
Synonyms: BAP-1,BAP1,DING,HIPI3,RING1B,RING2

Gene ID: 6045

NCBI Accession: NM_007212