MRPL12 antibody (AA 1-198)

Catalog No. ABIN562710

Product Details anti-MRPL12 Antibody

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Binding Specificity: AA 1-198

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MRPL12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a full length recombinant MRPL12.

Sequence: MLPAAARPLW GPCLGLRAAA FRLARRQVPC VCAVRHMRSS GHQRCEALAG APLDNAPKEY PPKIQQLVQD IASLTLLEIS DLNELLKKTL KIQDVGLVPM GGVMSGAVPA AAAQEAVEED IPIAKERTHF TVRLTEAKPV DKVKLIKEIK NYIQGINLVQ AKKLVESLPQ EIKANVAKAE AEKIKAALEA VGGTVVLE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MRPL12 (AAH02344, 1 a.a. ~ 198 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3B12-1A3

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MRPL12 antibody (ABIN562710)

Richman, Davies, Shearwood, Ermer, Scott, Hibbs, Rackham, Filipovska: "A bifunctional protein regulates mitochondrial protein synthesis." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5483-94, (2014) (PubMed).

Chen, Cairns, Papandreou, Koong, Denko: "Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect." in: PLoS ONE, Vol. 4, Issue 9, pp. e7033, (2009) (PubMed).

Wang, Cotney, Shadel: "Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 12610-8, (2007) (PubMed).

Target Details for MRPL12

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Alternative Name: MRPL12 (MRPL12 Products)

Background: Full Gene Name: mitochondrial ribosomal protein L12
Synonyms: 5c5-2,FLJ60124,L12mt,MGC8610,MRP-L31/34,MRPL7,MRPL7/L12,RPML12

Gene ID: 6182