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MRPL12 antibody

MRPL12 Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7074638
  • Target See all MRPL12 Antibodies
    MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))
    Reactivity
    • 34
    • 11
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 31
    • 3
    Rabbit
    Clonality
    • 32
    • 2
    Polyclonal
    Conjugate
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MRPL12 antibody is un-conjugated
    Application
    • 18
    • 13
    • 13
    • 13
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Mouse, Rat
    Purification
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Human MRPL12
    Top Product
    Discover our top product MRPL12 Primary Antibody
  • Application Notes
    WB (M,R) 1: 500-1: 1000, IHC/IF (H) 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))
    Alternative Name
    MRPL12 (MRPL12 Products)
    Synonyms
    5c5-2 antibody, L12mt antibody, MRP-L31/34 antibody, MRPL7 antibody, MRPL7/L12 antibody, RPML12 antibody, GB14723 antibody, MRPL12 antibody, 0610034O11Rik antibody, 1500031N16Rik antibody, MRP-L12 antibody, Rpml12 antibody, Rpm12 antibody, im:6893415 antibody, zgc:112445 antibody, mrpl12 antibody, mitochondrial ribosomal protein L12 antibody, 39S ribosomal protein L12, mitochondrial antibody, mitochondrial nucleoid protein antibody, mitochondrial ribosomal protein L12 L homeolog antibody, MRPL12 antibody, LOC409926 antibody, CAALFM_C207190CA antibody, Mrpl12 antibody, mrpl12 antibody, mrpl12.L antibody
    Background
    MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes, and is encoded by a nuclear gene. The protein forms a homodimer, localizes predominantly to mitochondria and binds to the large mitochondrial ribosomal subunit. It is required for CycD/Cdk4- induced cell growth. In addition, forming a ribosomal stalk with MRPL7, MRPL12 is required for the recruitment of translation elongation factors Tu and G to the large ribosomal subunit . It also a part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation and/or ribosome biogenesis during human mitochondrial gene expression.
    Molecular Weight
    21 kDa
    Gene ID
    56282
    NCBI Accession
    NP_081480
    UniProt
    Q9DB15
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