T-Box 5 antibody (AA 402-518)

Catalog No. ABIN563098

This Mouse Monoclonal antibody specifically detects T-Box 5 in WB, ELISA and RNAi. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for T-Box 5 antibody (AA 402-518) (ABIN563098)

Target: T-Box 5 (TBX5)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This T-Box 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, RNA Interference (RNAi)

Clone: 1G10

Product Details anti-T-Box 5 Antibody

Binding Specificity: AA 402-518

Purpose: Mouse monoclonal antibody raised against a partial recombinant TBX5.

Sequence: PSMPSYSSCT VTTVQPMDRL PYQHFSAHFT SGPLVPRLAG MANHGSPQLG EGMFQHQTSV AHQPVVRQCG PQTGLQSPGT LQPPEFLYSH GVPRTLSPHQ YHSVHGVGMV PEWSDNS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TBX5 (AAH27942, 402 a.a. ~ 518 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-T-Box 5 antibody (ABIN563098)

Baban, Pitto, Pulignani, Cresci, Mariani, Gambacciani, Digilio, Pongiglione, Albanese: "Holt-Oram syndrome with intermediate atrioventricular canal defect, and aortic coarctation: functional characterization of a de novo TBX5 mutation." in: American journal of medical genetics. Part A, Vol. 164A, Issue 6, pp. 1419-24, (2014) (PubMed).

Hartung, Schwanke, Haase, David, Franz, Martin, Zweigerdt: "Directing cardiomyogenic differentiation of human pluripotent stem cells by plasmid-based transient overexpression of cardiac transcription factors." in: Stem cells and development, Vol. 22, Issue 7, pp. 1112-25, (2013) (PubMed).

Ghosh, Song, Packham, Buxton, Robinson, Ronksley, Self, Bonser, Brook: "Physical interaction between TBX5 and MEF2C is required for early heart development." in: Molecular and cellular biology, Vol. 29, Issue 8, pp. 2205-18, (2009) (PubMed).

Target Details for T-Box 5

Target: T-Box 5 (TBX5)

Alternative Name: TBX5

Background: Full Gene Name: T-box 5
Synonyms: HOS

Gene ID: 6910