TWIST1 antibody (AA 100-202)

Catalog No. ABIN563296

This Mouse Monoclonal antibody specifically detects TWIST1 in WB, ELISA, IP and RNAi. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for TWIST1 antibody (AA 100-202) (ABIN563296)

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TWIST1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), RNA Interference (RNAi)

Clone: 3E11

Product Details anti-TWIST1 Antibody

Binding Specificity: AA 100-202

Purpose: Mouse monoclonal antibody raised against a partial recombinant TWIST1.

Sequence: PQSYEELQTQ RVMANVRERQ RTQSLNEAFA ALRKIIPTLP SDKLSKIQTL KLAARYIDFL YQVLQSDELD SKMASCSYVA HERLSYAFSV WRMEGAWSMS ASH

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TWIST1 (NP_000465, 100 a.a. ~ 202 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TWIST1 antibody (ABIN563296)

Schaeffer, Somarelli, Hanna, Palmer, Garcia-Blanco: "Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition." in: Molecular and cellular biology, Vol. 34, Issue 18, pp. 3486-99, (2014) (PubMed).

Bornachea, Santos, Martínez-Cruz, García-Escudero, Dueñas, Costa, Segrelles, Lorz, Buitrago, Saiz-Ladera, Agirre, Grande, Paradela, Maraver, Ariza, Prosper, Serrano, Sánchez-Céspedes, Paramio: "EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours." in: Scientific reports, Vol. 2, pp. 434, (2012) (PubMed).

Saito, Murata-Kamiya, Hirayama, Ohba, Hatakeyama: "Conversion of Helicobacter pylori CagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21." in: The Journal of experimental medicine, Vol. 207, Issue 10, pp. 2157-74, (2010) (PubMed).

Target Details for TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Alternative Name: TWIST1

Background: Full Gene Name: twist homolog 1 (Drosophila)
Synonyms: ACS3,BPES2,BPES3,SCS,TWIST,bHLHa38

Gene ID: 7291

NCBI Accession: NM_000474

Pathways: p53 Signaling, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity