ube3a antibody (AA 51-150)

Catalog No. ABIN563326

This Mouse Monoclonal antibody specifically detects ube3a in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for ube3a antibody (AA 51-150) (ABIN563326)

Target: ube3a (Ubiquitin Protein Ligase E3A (ube3a))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ube3a antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2F6

Product Details anti-ube3a Antibody

Binding Specificity: AA 51-150

Purpose: Mouse monoclonal antibody raised against a partial recombinant UBE3A.

Sequence: ETFQQLITYK VISNEFNSRN LVNDDDAIVA ASKCLKMVYY ANVVGGEVDT NHNEEDDEEP IPESSELTLQ ELLGEERRNK KGPRVDPLET ELGVKTLDCR

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: UBE3A (AAH09271, 51 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ube3a antibody (ABIN563326)

Underbrink, Howie, Bedard, Koop, Galloway: "E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation." in: Journal of virology, Vol. 82, Issue 21, pp. 10408-17, (2008) (PubMed).

Target Details for ube3a

Target: ube3a (Ubiquitin Protein Ligase E3A (ube3a))

Alternative Name: UBE3A

Background: Full Gene Name: ubiquitin protein ligase E3A
Synonyms: ANCR,AS,E6-AP,EPVE6AP,FLJ26981,HPVE6A

Gene ID: 7337

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway