PDE5A antibody (AA 29-138)

Catalog No. ABIN563734

This Mouse Polyclonal antibody specifically detects PDE5A in ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for PDE5A antibody (AA 29-138) (ABIN563734)

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PDE5A antibody is un-conjugated

Application: ELISA

Product Details anti-PDE5A Antibody

Binding Specificity: AA 29-138

Purpose: Mouse polyclonal antibody raised against a partial recombinant PDE5A.

Sequence: SVEAWLDDHW DFTFSYFVRK ATREMVNAWF AERVHTIPVC KEGIRGHTES CSCPLQQSPR ADNSVPGTPT RKISASEFDR PLRPIVVKDS EGTVSFLSDS EKKEQMPLTP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PDE5A (NP_001074, 29 a.a. ~ 138 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PDE5A antibody (ABIN563734)

Meyer, Sevko, Ramacher, Bazhin, Falk, Osen, Borrello, Kato, Schadendorf, Baniyash, Umansky: "Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 41, pp. 17111-6, (2011) (PubMed).

Target Details for PDE5A

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Alternative Name: PDE5A

Background: Full Gene Name: phosphodiesterase 5A, cGMP-specific
Synonyms: CGB-PDE,CN5A,PDE5,PDE5A1

Gene ID: 8654

NCBI Accession: NM_001083

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling