CDC42BPB antibody (AA 1580-1679)

Catalog No. ABIN564131

There are 3+ publications for this product available. The Mouse Polyclonal anti-CDC42BPB antibody is suitable to detect CDC42BPB in samples from Human. It has been validated for ELISA and WB.

Quick Overview for CDC42BPB antibody (AA 1580-1679) (ABIN564131)

Target: CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This CDC42BPB antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CDC42BPB Antibody

Binding Specificity: AA 1580-1679

Purpose: Mouse polyclonal antibody raised against a partial recombinant CDC42BPB.

Sequence: SKMISNPTNF NHVAHMGPGD GMQVLMDLPL SAVPPSQEER PGPAPTNLAR QPPSRNKPYI SWPSSGGSEP SVTVPLRSMS DPDQDFDKEP DSDSTKHSTP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CDC42BPB (AAD37506, 1580 a.a. ~ 1679 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CDC42BPB antibody (ABIN564131)

Unbekandt, Croft, Crighton, Mezna, McArthur, McConnell, Schüttelkopf, Belshaw, Pannifer, Sime, Bower, Drysdale, Olson: "A novel small-molecule MRCK inhibitor blocks cancer cell invasion." in: Cell communication and signaling : CCS, Vol. 12, pp. 54, (2015) (PubMed).

Heikkila, Wheatley, Crighton, Schroder, Boakes, Kaye, Mezna, Pang, Rushbrooke, Turnbull, Olson: "Co-crystal structures of inhibitors with MRCK?, a key regulator of tumor cell invasion." in: PLoS ONE, Vol. 6, Issue 9, pp. e24825, (2011) (PubMed).

Adachi, Kano, Saido, Murata: "Visual screening and analysis for kinase-regulated membrane trafficking pathways that are involved in extensive beta-amyloid secretion." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 14, Issue 3, pp. 355-69, (2009) (PubMed).

Target Details for CDC42BPB

Target: CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))

Alternative Name: CDC42BPB

Background: Full Gene Name: CDC42 binding protein kinase beta (DMPK-like)
Synonyms: KIAA1124,MRCKB

Gene ID: 9578