LLGL2 antibody (AA 940-973)

Catalog No. ABIN7479891

This Rabbit Polyclonal antibody specifically detects LLGL2 in WB. It exhibits reactivity toward Human.

Quick Overview for LLGL2 antibody (AA 940-973) (ABIN7479891)

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LLGL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LLGL2 Antibody

Binding Specificity: AA 940-973

Purpose: LLGL2 Antibody / HGL

Purification: SAS precipitation followed by dialysis in PBS

Immunogen: A portion of amino acids 940-973 from the human protein was used as the immunogen for the LLGL2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the LLGL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the LLGL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LLGL2

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Alternative Name: LLGL2

Background: The lethal (2) giant larvae protein of Drosophila / Human giant larvae homolog plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

UniProt: Q6P1M3

Pathways: WNT Signaling