FGG antibody (AA 133-163)

Catalog No. ABIN5647118

This anti-FGG antibody is a Rabbit Polyclonal antibody detecting FGG in WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for FGG antibody (AA 133-163) (ABIN5647118)

Target: FGG (Fibrinogen gamma Chain (FGG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FGG Antibody

Binding Specificity: AA 133-163

Purification: Antigen affinity purified

Immunogen: Amino acids 133-163 (IRYLQEIYNSNNQKIVNLKEKVAQLEAQCQE-human) were used as the immunogen for the Fibrinogen gamma chain antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Fibrinogen gamma chain antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Fibrinogen gamma chain antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FGG

Target: FGG (Fibrinogen gamma Chain (FGG))

Background: Fibrinogen gamma chain, also known as FGG, is a human gene found on chromosome 4. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.

UniProt: P02679