Thymic Stromal Lymphopoietin antibody

Catalog No. ABIN5647286

The Rabbit Polyclonal anti-Thymic Stromal Lymphopoietin antibody (ABIN5647286) specifically detects Thymic Stromal Lymphopoietin in WB and ELISA (Capture). The antibody is reactive with Human and Mouse samples.

Quick Overview for Thymic Stromal Lymphopoietin antibody (ABIN5647286)

Target: Thymic Stromal Lymphopoietin (TSLP)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thymic Stromal Lymphopoietin antibody is un-conjugated

Application: Western Blotting (WB), ELISA (Capture)

Product Details anti-Thymic Stromal Lymphopoietin Antibody

Purification: Antigen affinity purified

Immunogen: Amino acids KVTTNKCLEQVSQLQGLWRRFNRPLLKQQ were used as the immunogen for the TSLP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TSLP antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the TSLP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Thymic Stromal Lymphopoietin

Target: Thymic Stromal Lymphopoietin (TSLP)

Alternative Name: TSLP

Background: Thymic stromal lymphopoietin, also called TSLP is a protein belonging to the cytokine family. This gene is mapped to 5q22.1. It encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2(TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases.

UniProt: Q969D9