Cytokeratin 5 antibody (AA 286-317)

Catalog No. ABIN5647372

The Rabbit Polyclonal anti-Cytokeratin 5 antibody has been validated for WB and IHC (p). It is suitable to detect Cytokeratin 5 in samples from Human, Mouse and Rat.

Quick Overview for Cytokeratin 5 antibody (AA 286-317) (ABIN5647372)

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cytokeratin 5 Antibody

Binding Specificity: AA 286-317

Purification: Antigen affinity purified

Immunogen: Amino acids 286-317 (KVELEAKVDALMDEINFMKMFFDAELSQMQTH-human) were used as the immunogen for the Cytokeratin 5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cytokeratin 5 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Cytokeratin 5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Alternative Name: Cytokeratin 5

Background: Cytokeratin 5, also known as Keratin 5, KRT5, K5, or CK5, is a protein that is encoded in humans by the KRT5 gene. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

UniProt: P13647