Western blot: 1:500-1000,IHC (Paraffin): 1:10-1:50
Restrictions
For Research Use only
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the ACO2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
ACO2
(Aconitase 2, Mitochondrial (ACO2))
Alternative Name
Aconitase 2
Background
Aconitase 2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.