Titration of the ACO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the ACO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
ACO2
(Aconitase 2, Mitochondrial (ACO2))
Alternative Name
ACO2
Background
Aconitase 2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.