ACO2 antibody (AA 438-467)

Catalog No. ABIN7479755

This Rabbit Polyclonal antibody specifically detects ACO2 in WB, ELISA and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ACO2 antibody (AA 438-467) (ABIN7479755)

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ACO2 Antibody

Binding Specificity: AA 438-467

Purpose: Aconitase 2 Antibody

Cross-Reactivity (Details): Expected species reactivity: Bovine,Pig

Purification: Purified

Immunogen: A portion of amino acids 438-467 from the human protein was used as the immunogen for this Aconitase 2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Aconitase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Aconitase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ACO2

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Alternative Name: Aconitase 2

Background: ACO2/Aconitase 2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

UniProt: Q99798