ACCN4 antibody (AA 23-52)

Catalog No. ABIN5647477

Product Details anti-ACCN4 Antibody

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Binding Specificity: AA 23-52

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACCN4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 23-52 from the human protein was used as the immunogen for this ASIC4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Western blot: 1:1000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ASIC4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ACCN4

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Alternative Name: ACCN4 / ASIC4 (ACCN4 Products)

Synonyms: ACCN4 antibody, BNAC4 antibody, Accn4 antibody, Spasic antibody, acid sensing ion channel subunit family member 4 S homeolog antibody, acid sensing ion channel subunit family member 4 antibody, acid-sensing (proton-gated) ion channel family member 4 antibody, asic4.S antibody, ASIC4 antibody, Asic4 antibody

Background: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.

UniProt: Q96FT7