alpha 2 Macroglobulin antibody (AA 93-120)

Catalog No. ABIN7479743

The Rabbit Polyclonal anti-alpha 2 Macroglobulin antibody is suitable to detect alpha 2 Macroglobulin in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for alpha 2 Macroglobulin antibody (AA 93-120) (ABIN7479743)

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha 2 Macroglobulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-alpha 2 Macroglobulin Antibody

Binding Specificity: AA 93-120

Purpose: Alpha-2-macroglobulin Antibody

Cross-Reactivity (Details): Expected species reactivity: Bovine

Purification: Antigen affinity

Immunogen: A portion of amino acids 93-120 from the human protein was used as the immunogen for this Alpha-2-macroglobulin antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Alpha-2-macroglobulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Alpha-2-macroglobulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for alpha 2 Macroglobulin

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Alternative Name: Alpha-2-macroglobulin

Background: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].

UniProt: P01023

Pathways: Lipid Metabolism