MLLT11 antibody (AA 1-90)
Quick Overview for MLLT11 antibody (AA 1-90) (ABIN564754)
Target
See all MLLT11 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-90
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Purpose
- Mouse monoclonal antibody raised against a full length recombinant AF1Q.
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Sequence
- MRDPVSSQYS SFLFWRMPIP ELDLSELEGL GLSDTATYKV KDSSVGKMIG QATAADQEKN PEGDGLLEYS TFNFWRAPIA SIHSFELDLL
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Cross-Reactivity
- Human
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Characteristics
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- AF1Q (AAH09624, 1 a.a. ~ 90 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotype
- IgG2a
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Application Notes
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Suggested Applications*:elisa,western blotting
*We do not guarantee this product working for suggested applications.
Optimal working dilution should be determined by the investigator. -
Restrictions
- For Research Use only
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Buffer
- In 1x PBS, pH 7.4
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "MLLT11/AF1q is differentially expressed in maturing neurons during development." in: Gene expression patterns : GEP, Vol. 15, Issue 2, pp. 80-7, (2014) (PubMed).
: "AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells." in: PLoS ONE, Vol. 7, Issue 6, pp. e39968, (2012) (PubMed).
: "AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway." in: Blood, Vol. 118, Issue 7, pp. 1784-96, (2011) (PubMed).
: "Identification of the functional role of AF1Q in the progression of breast cancer." in: Breast cancer research and treatment, Vol. 111, Issue 1, pp. 65-78, (2008) (PubMed).
: "Oncogene AF1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway." in: Molecular cancer therapeutics, Vol. 7, Issue 10, pp. 3160-8, (2008) (PubMed).
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- MLLT11 (Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
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Alternative Name
- MLLT11
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Background
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Full Gene Name: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 11
Synonyms: AF1Q,RP11-316M1.10 -
Gene ID
- 10962
Target
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