FGFR1 antibody (AA 489-520)

Catalog No. ABIN5647574

This anti-FGFR1 antibody is a Rabbit Polyclonal antibody detecting FGFR1 in WB. Suitable for Human.

Quick Overview for FGFR1 antibody (AA 489-520) (ABIN5647574)

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGFR1 Antibody

Binding Specificity: AA 489-520

Purification: Antigen affinity purified

Immunogen: Amino acids 489-520 (FGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDA-human) were used as the immunogen for the FGFR1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the FGFR1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the FGFR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FGFR1

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Alternative Name: FGFR1 / Fibroblast growth factor receptor 1

Background: FGFR1, Fibroblast growth factor receptor 1, also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. The FGFR1 gene is localized to 8p12-p11.2 by in situ hybridization. FGFR1 is essential for the normal formation of the organ of Corti and that phenotype severity observed in FGFR1 mutants is dependent on the dose of FGFR1. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome 2.

UniProt: P11362

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins