AQP11 antibody (AA 35-70)

Catalog No. ABIN5647736

The Rabbit Polyclonal anti-AQP11 antibody (ABIN5647736) specifically detects AQP11 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for AQP11 antibody (AA 35-70) (ABIN5647736)

Target: AQP11 (Aquaporin 11 (AQP11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQP11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AQP11 Antibody

Binding Specificity: AA 35-70

Purpose: AQP11 Antibody / Aquaporin 11

Purification: Antigen affinity

Immunogen: Amino acids 35-70 (ARQQLHRPVAHAFVLEFLATFQLCCCTHELQLLSEQ from the human protein were used as the immunogen for the AQP11 antibody.

Isotype: IgG

Application Details

Application Notes: Differences in protocols and secondary/substrate sensitivity may require the AQP11 antibody to be titrated for optimal performance.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the AQP11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for AQP11

Target: AQP11 (Aquaporin 11 (AQP11))

Alternative Name: AQP11

Background: AQP11 has a unique asparagine-proline-alanine (NPA) box distinct from those of other AQPs, suggesting a different pore structure and function. Using Northern blot analysis, they detected highest expression of mouse Aqp11 in testis, followed by liver and kidney. Expression was much weaker in heart, brain, and muscle. Western blot analysis of mouse kidney membrane fractions detected Aqp11 at an apparent molecular mass of 26 kD, lower than the calculated molecular mass of 30 kD. Immunohistochemical analysis localized Aqp11 to mouse renal proximal tubule cells, where it showed a perinuclear distribution. Fluorescence-tagged Aqp11 localized with an endoplasmic reticulum marker.

UniProt: Q8NBQ7