GLA antibody (AA 218-275)

Catalog No. ABIN5647751

The Rabbit Polyclonal anti-GLA antibody (ABIN5647751) specifically detects GLA in WB. The antibody is reactive with Mouse samples.

Quick Overview for GLA antibody (AA 218-275) (ABIN5647751)

Target: GLA (Galactosidase, alpha (GLA))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLA Antibody

Binding Specificity: AA 218-275

Purification: Antigen affinity purified

Immunogen: Amino acids 218-275 (DIQYYCNHWRNFDDVYDSWESIKNILSWTVVYQKEIVEVA-mouse) were used as the immunogen for the Gla antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Gla antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Gla antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for GLA

Target: GLA (Galactosidase, alpha (GLA))

Alternative Name: Gla / Galactosidase alpha

Background: Alpha-galactosidase is a glycoside hydrolase enzyme that encoded by the GLA gene. This gene is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

UniProt: P51569

Pathways: SARS-CoV-2 Protein Interactome