FERMT3
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
Western blot: 1:1000-2000
Restrictions
For Research Use only
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the Kindlin-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
FERMT3
(Fermitin Family Member 3 (FERMT3))
Alternative Name
Kindlin-3 / URP2 / FERMT3
Background
Fermitin family homolog 3, also called Kindlin-3, plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).