FERMT3 antibody

Catalog No. ABIN7232050

This Rabbit Polyclonal antibody specifically detects FERMT3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for FERMT3 antibody (ABIN7232050)

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FERMT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FERMT3 Antibody

Purpose: Rabbit Anti-URP2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of URP2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human URP2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FERMT3

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Alternative Name: URP2

Background: Fermitin family homolog 3, Kindlin-3, MIG2-like protein, Unc-112-related protein 2Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 73kD

Gene ID: 83706

UniProt: Q86UX7