Peptide YY antibody (AA 29-64)

Catalog No. ABIN5647902

This Rabbit Polyclonal antibody specifically detects Peptide YY in IF and IHC (p). It exhibits reactivity toward Rat and Mouse.

Quick Overview for Peptide YY antibody (AA 29-64) (ABIN5647902)

Target: Peptide YY (PYY)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peptide YY antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Peptide YY Antibody

Binding Specificity: AA 29-64

Purpose: PYY Antibody / Peptide YY

Sequence: YPAKPEAPGE DASPEELSRY YASLRHYLNL VTRQRY

Purification: Antigen affinity

Immunogen: Amino acids 29-64 (YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY) from the mouse protein were used as the immunogen for the PYY antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PYY antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: Prior to reconstitution, store at 4oC. After reconstitution, the PYY antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Peptide YY

Target: Peptide YY (PYY)

Alternative Name: PYY

Background: Peptide YY (PYY), also known as peptide tyrosine tyrosine, is a peptide that in humans is encoded by the PYY gene. This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa.

UniProt: Q9EPS2