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PVRL4 antibody (AA 53-94)

PVRL4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5647906
  • Target See all PVRL4 Antibodies
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 53-94
    Reactivity
    • 48
    • 22
    • 14
    Human
    Host
    • 43
    • 5
    • 2
    Rabbit
    Clonality
    • 44
    • 5
    • 1
    Polyclonal
    Conjugate
    • 23
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PVRL4 antibody is un-conjugated
    Application
    • 46
    • 28
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity purified
    Immunogen
    Amino acids 53-94 (FYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAY) from the human protein were used as the immunogen for the Nectin-4 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product PVRL4 Primary Antibody
  • Application Notes
    Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the Nectin-4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    Alternative Name
    Nectin-4 / PVRL4 (PVRL4 Products)
    Synonyms
    PVRL4 antibody, si:ch211-155e24.1 antibody, 1200017F15Rik antibody, Prr4 antibody, RGD1559826 antibody, EDSS1 antibody, LNIR antibody, PRR4 antibody, nectin-4 antibody, nectin cell adhesion molecule 4 antibody, NECTIN4 antibody, nectin4 antibody, Nectin4 antibody
    Background
    PVRL4, also known as Nectin-4, is expressed in human skin, hair follicles, and cultured keratinocytes, but not in fibroblasts. This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
    UniProt
    Q96NY8
    Pathways
    Cell-Cell Junction Organization
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