AANAT antibody (AA 27-54)

Catalog No. ABIN7479786

The Rabbit Polyclonal anti-AANAT antibody (ABIN7479786) specifically detects AANAT in ELISA and WB. The antibody is reactive with Human samples.

Quick Overview for AANAT antibody (AA 27-54) (ABIN7479786)

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AANAT antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-AANAT Antibody

Binding Specificity: AA 27-54

Purpose: AANAT Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 27-54 from the human protein was used as the immunogen for this AANAT antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the AANAT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the AANAT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for AANAT

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Alternative Name: AANAT

Background: Serotonin N-acetyltransferase/AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.

UniProt: Q16613

Pathways: Photoperiodism