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AANAT antibody (AA 27-54)
AANAT
Reactivity: Human
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-AANAT Antibody
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Target
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AANAT
(Aralkylamine N-Acetyltransferase (AANAT))
Binding Specificity
All epitopes for AANAT antibodies
AA 27-54
Reactivity
All reactivities for AANAT antibodies
Human
Host
All hosts for AANAT antibodies
Rabbit
Clonality
All clonalities for AANAT antibodies
Polyclonal
Conjugate
All conjugates for AANAT antibodies
This AANAT antibody is un-conjugated
Application
All applications for AANAT antibodies
ELISA, Western Blotting (WB)
Purification
Antigen affinity purified
Immunogen
A portion of amino acids 27-54 from the human protein was used as the immunogen for this AANAT antibody.
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Western blot: 1:1000
Restrictions
For Research Use only
Handling
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Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the AANAT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for AANAT
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Target
AANAT
(Aralkylamine N-Acetyltransferase (AANAT))
Alternative Name
AANAT (AANAT Products )
Synonyms
DSPS antibody, SNAT antibody, AA-NAT antibody, Nat4 antibody, Nat-2 antibody, Snat antibody, aralkylamine N-acetyltransferase antibody, arylalkylamine N-acetyltransferase antibody, AANAT antibody, Aanat antibody
Background
Serotonin N-acetyltransferase/AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.
UniProt
Q16613
Pathways
Photoperiodism
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