BAMBI antibody (AA 1-260)

Catalog No. ABIN565170

Product Details anti-BAMBI Antibody

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Binding Specificity: AA 1-260

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAMBI antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a full length recombinant BAMBI.

Sequence: MDRHSSYIFI WLQLELCAMA VLLTKGEIRC YCDAAHCVAT GYMCKSELSA CFSRLLDPQN SNSPLTHGCL DSLASTTDIC QAKQARNHSG TTIPTLECCH EDMCNYRGLH DVLSPPRGEA SGQGNRYQHD GSRNLITKVQ ELTSSKELWF RAAVIAVPIA GGLTLVLLIM LALRMLRSEN KRLQDQRQQM LSRLHYSFHG HHSKKGQVAK LDLECMVPVS GHENCCLTCD KMRQADLSND KILSLVHWGM YSGHGKLEFV

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: BAMBI (AAH19252, 1 a.a. ~ 260 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3C1-1D1

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-BAMBI antibody (ABIN565170)

Wanninger, Neumeier, Bauer, Weiss, Eisinger, Walter, Dorn, Hellerbrand, Schäffler, Buechler: "Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes." in: FEBS letters, Vol. 585, Issue 9, pp. 1338-44, (2011) (PubMed).

Tramullas, Lantero, Díaz, Morchón, Merino, Villar, Buscher, Merino, Hurlé, Izpisúa-Belmonte, Hurlé: "BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 4, pp. 1502-11, (2010) (PubMed).

Pils, Wittinger, Petz, Gugerell, Gregor, Alfanz, Horvat, Braicu, Sehouli, Zeillinger, Mikulits, Krainer: "BAMBI is overexpressed in ovarian cancer and co-translocates with Smads into the nucleus upon TGF-beta treatment." in: Gynecologic oncology, Vol. 117, Issue 2, pp. 189-97, (2010) (PubMed).

Xavier, Gilbert, Rastaldi, Krick, Kollins, Reddy, Bottinger, Cohen, Schlondorff: "BAMBI is expressed in endothelial cells and is regulated by lysosomal/autolysosomal degradation." in: PLoS ONE, Vol. 5, Issue 9, pp. e12995, (2010) (PubMed).

Target Details for BAMBI

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Alternative Name: BAMBI (BAMBI Products)

Background: Full Gene Name: BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
Synonyms: NMA

Gene ID: 25805