FBXW8 antibody (AA 499-598)

Catalog No. ABIN565252

This Mouse Polyclonal antibody specifically detects FBXW8 in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for FBXW8 antibody (AA 499-598) (ABIN565252)

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This FBXW8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FBXW8 Antibody

Binding Specificity: AA 499-598

Purpose: Mouse polyclonal antibody raised against a partial recombinant FBXW8.

Sequence: VWDYRMNQKL WEVYSGHPVQ HISFSSHSLI TANVPYQTVM RNADLDSFTT HRRHRGLIRA YEFAVDQLAF QSPLPVCRSS CDAMATHYYD LALAFPYNHV

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FBXW8 (NP_699179, 499 a.a. ~ 598 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FBXW8 antibody (ABIN565252)

Achiwa, Hasegawa, Udagawa: "Effect of ursolic acid on MAPK in cyclin D1 signaling and RING-type E3 ligase (SCF E3s) in two endometrial cancer cell lines." in: Nutrition and cancer, Vol. 65, Issue 7, pp. 1026-33, (2013) (PubMed).

Wei, Yang, Chuang, Yang, Kulp, Lu, Lai, Chen: "A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 39, pp. 26759-70, (2008) (PubMed).

Target Details for FBXW8

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Alternative Name: FBXW8

Background: Full Gene Name: F-box and WD repeat domain containing 8
Synonyms: FBW6,FBW8,FBX29,FBXO29,FBXW6,MGC33534

Gene ID: 26259

NCBI Accession: NM_153348