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ABHD5 antibody (AA 1-349)

ABHD5 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1F3 unconjugated
Catalog No. ABIN565526
  • Target See all ABHD5 Antibodies
    ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))
    Binding Specificity
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-349
    Reactivity
    • 28
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 23
    • 5
    • 1
    Mouse
    Clonality
    • 25
    • 4
    Monoclonal
    Conjugate
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABHD5 antibody is un-conjugated
    Application
    • 16
    • 13
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Mouse monoclonal antibody raised against a full length recombinant ABHD5.
    Sequence
    MAAEEEEVDS ADTGERSGWL TGWLPTWCPT SISHLKEAEE KMLKCVPCTY KKEPVRISNG NKIWTLKFSH NISNKTPLVL LHGFGGGLGL WALNFGDLCT NRPVYAFDLL GFGRSSRPRF DSDAEEVENQ FVESIEEWRC ALGLDKMILL GHNLGGFLAA AYSLKYPSRV NHLILVEPWG FPERPDLADQ DRPIPVWIRA LGAALTPFNP LAGLRIAGPF GLSLVQRLRP DFKRKYSSMF EDDTVTEYIY HCNVQTPSGE TAFKNMTIPY GWAKRPMLQR IGKMHPDIPV SVIFGARSCI DGNSGTSIQS LRPHSYVKTI AILGAGHYVY ADQPEEFNQK VKEICDTVD
    Cross-Reactivity
    Human, Rat
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    ABHD5 (AAH21958, 1 a.a. ~ 349 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1F3
    Isotype
    IgG2a
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Hofer, Boeszoermenyi, Jaeger, Feiler, Arthanari, Mayer, Zehender, Rechberger, Oberer, Zimmermann, Lass, Haemmerle, Breinbauer, Zechner, Preiss-Landl: "Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling." in: The Journal of biological chemistry, Vol. 290, Issue 30, pp. 18438-53, (2015) (PubMed).

    Kurtz, Peck, Fannin, Beysen, Miao, Landstreet, Ding, Turaga, Lund, Turner, Biddinger, Vickers, Sethupathy: "MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes." in: Diabetes, Vol. 63, Issue 9, pp. 3141-8, (2014) (PubMed).

    Patel, Yang, Kozusko, Saudek, Savage: "Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 involved in sequestering ABHD5 and suppressing basal lipolysis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 25, pp. 9163-8, (2014) (PubMed).

    Camus, Schweiger, Herker, Harris, Kondratowicz, Tsou, Farese, Herath, Previs, Roddy, Pinto, Zechner, Ott et al.: "The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid ..." in: The Journal of biological chemistry, Vol. 289, Issue 52, pp. 35770-80, (2014) (PubMed).

    Pollak, Schweiger, Jaeger, Kolb, Kumari, Schreiber, Kolleritsch, Markolin, Grabner, Heier, Zierler, Rülicke, Zimmermann, Lass, Zechner, Haemmerle: "Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier." in: Journal of lipid research, Vol. 54, Issue 4, pp. 1092-102, (2013) (PubMed).

    Guo, Ma, Kadegowda, Betters, Xie, Liu, Liu, Miao, Ou, Su, Zheng, Xue, Shi, Yu: "Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice." in: Journal of lipid research, Vol. 54, Issue 8, pp. 2109-20, (2013) (PubMed).

    Louche, Badin, Montastier, Laurens, Bourlier, de Glisezinski, Thalamas, Viguerie, Langin, Moro: "Endurance exercise training up-regulates lipolytic proteins and reduces triglyceride content in skeletal muscle of obese subjects." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 12, pp. 4863-71, (2013) (PubMed).

    Inoue, Kobayashi, Inoguchi, Sonoda, Maeda, Hirata, Fujimura, Miura, Hirano, Takayanagi: "Downregulation of adipose triglyceride lipase in the heart aggravates diabetic cardiomyopathy in db/db mice." in: Biochemical and biophysical research communications, Vol. 438, Issue 1, pp. 224-9, (2013) (PubMed).

    Grall, Guaguère, Planchais, Grond, Bourrat, Hausser, Hitte, Le Gallo, Derbois, Kim, Lagoutte, Degorce-Rubiales, Radner, Thomas, Küry, Bensignor, Fontaine, Pin, Zimmermann, Zechner, Lathrop, Galibert et al.: "PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. ..." in: Nature genetics, Vol. 44, Issue 2, pp. 140-7, (2012) (PubMed).

    Stenson, Rydén, Venteclef, Dahlman, Pettersson, Mairal, Aström, Blomqvist, Wang, Jocken, Clément, Langin, Arner, Laurencikiene: "Liver X receptor (LXR) regulates human adipocyte lipolysis." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 370-9, (2011) (PubMed).

    Kinney, Qiao, Levaugh, Shao: "B56alpha/protein phosphatase 2A inhibits adipose lipolysis in high-fat diet-induced obese mice." in: Endocrinology, Vol. 151, Issue 8, pp. 3624-32, (2010) (PubMed).

  • Target
    ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))
    Alternative Name
    ABHD5 (ABHD5 Products)
    Synonyms
    ABHD5 antibody, cds antibody, cgi58 antibody, iecn2 antibody, ncie2 antibody, abhd5 antibody, CDS antibody, CGI58 antibody, IECN2 antibody, NCIE2 antibody, 1300003D03Rik antibody, 2010002J10Rik antibody, CGI-58 antibody, IECN5 antibody, abhydrolase domain containing 5 antibody, abhydrolase domain containing 5a antibody, abhydrolase domain containing 5 L homeolog antibody, ABHD5 antibody, abhd5 antibody, abhd5a antibody, Abhd5 antibody, abhd5.L antibody
    Background
    Full Gene Name: abhydrolase domain containing 5
    Synonyms: CDS,CGI58,IECN2,MGC8731,NCIE2
    Gene ID
    51099
    Pathways
    Lipid Metabolism
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