ZAK antibody (AA 1-120)

Catalog No. ABIN565679

There are 3+ publications for this product available. The Mouse Monoclonal anti-ZAK antibody is suitable to detect ZAK in samples from Human. It has been validated for WB, ELISA, IF and IHC (p).

Quick Overview for ZAK antibody (AA 1-120) (ABIN565679)

Target: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZAK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3G5

Product Details anti-ZAK Antibody

Binding Specificity: AA 1-120

Purpose: Mouse monoclonal antibody raised against a partial recombinant ZAK.

Sequence: MSSLGASFVQ IKFDDLQFFE NCGGGSFGSV YRAKWISQDK EVAVKKLLKI EKEAEILSVL SHRNIIQFYG VILEPPNYGI VTEYASLGSL YDYINSNRSE EMDMDHIMTW ATDVAKGMHY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ZAK (AAH01401, 1 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ZAK antibody (ABIN565679)

Nyati, Chator, Schinske, Gregg, Ross, Rehemtulla: "A Requirement for ZAK Kinase Activity in Canonical TGF-β Signaling." in: Translational oncology, Vol. 9, Issue 6, pp. 473-481, (2016) (PubMed).

Pérez López, Cariolato, Maric, Gillet, Abriel, Diviani: "A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy." in: Molecular and cellular biology, Vol. 33, Issue 15, pp. 2903-17, (2013) (PubMed).

Cariolato, Cavin, Diviani: "A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in ?1-adrenergic receptor-induced p38 activation." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 7925-37, (2011) (PubMed).

Target Details for ZAK

Target: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Alternative Name: ZAK

Background: Full Gene Name: sterile alpha motif and leucine zipper containing kinase AZK
Synonyms: AZK,MLK7,MLT,MLTK,MRK,mlklak

Gene ID: 51776