EGLN1 antibody (AA 272-355)

Catalog No. ABIN565755

Cited in 1 publication. The Mouse Polyclonal anti-EGLN1 antibody (ABIN565755) specifically detects EGLN1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for EGLN1 antibody (AA 272-355) (ABIN565755)

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This EGLN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EGLN1 Antibody

Binding Specificity: AA 272-355

Purpose: Mouse polyclonal antibody raised against a partial recombinant EGLN1.

Sequence: LMSSMDDLIR HCNGKLGSYK INGRTKAMVA CYPGNGTGYV RHVDNPNGDG RCVTCIYYLN KDWDAKVSGG ILRIFPEGKA QFAD

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: EGLN1 (NP_071334, 272 a.a. ~ 355 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-EGLN1 antibody (ABIN565755)

Aprelikova, Pandolfi, Tackett, Ferreira, Salnikow, Ward, Risinger, Barrett, Niederhuber: "Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response." in: Cancer research, Vol. 69, Issue 2, pp. 616-24, (2009) (PubMed).

Target Details for EGLN1

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Alternative Name: EGLN1

Background: Full Gene Name: egl nine homolog 1 (C. elegans)
Synonyms: C1orf12,DKFZp761F179,ECYT3,HIFPH2,HPH2,PHD2,SM-20,SM20,ZMYND6

Gene ID: 54583

NCBI Accession: NM_022051

Pathways: cAMP Metabolic Process, Warburg Effect