VPS35 antibody (AA 697-796)

Catalog No. ABIN565910

There are 3+ publications for this product available. The Mouse Monoclonal anti-VPS35 antibody is suitable to detect VPS35 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for VPS35 antibody (AA 697-796) (ABIN565910)

Target: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VPS35 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2D3

Product Details anti-VPS35 Antibody

Binding Specificity: AA 697-796

Purpose: Mouse monoclonal antibody raised against a partial recombinant VPS35.

Sequence: MECLKKALKI ANQCMDPSLQ VQLFIEILNR YIYFYEKEND AVTIQVLNQL IQKIREDLPN LESSEETEQI NKHFHNTLEH LRLRRESPES EGPIYEGLIL

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: VPS35 (NP_060676, 697 a.a. ~ 796 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-VPS35 antibody (ABIN565910)

Munsie, Milnerwood, Seibler, Beccano-Kelly, Tatarnikov, Khinda, Volta, Kadgien, Cao, Tapia, Klein, Farrer: "Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N." in: Human molecular genetics, Vol. 24, Issue 6, pp. 1691-703, (2015) (PubMed).

Kang, Ge, Cassidy, Lam, Luo, Moon, Lewis, Molday, Wong, Foster, Craig: "A combined transgenic proteomic analysis and regulated trafficking of neuroligin-2." in: The Journal of biological chemistry, Vol. 289, Issue 42, pp. 29350-64, (2014) (PubMed).

Prosser, Tran, Schooley, Wendland, Ngsee: "A novel, retromer-independent role for sorting nexins 1 and 2 in RhoG-dependent membrane remodeling." in: Traffic (Copenhagen, Denmark), Vol. 11, Issue 10, pp. 1347-62, (2010) (PubMed).

Target Details for VPS35

Target: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Alternative Name: VPS35

Background: Full Gene Name: vacuolar protein sorting 35 homolog (S. cerevisiae)
Synonyms: DKFZp434E1211,DKFZp434P1672,FLJ10752,FLJ13588,FLJ20388,MEM3

Gene ID: 55737

NCBI Accession: NM_018206