Gastrokine 1 antibody (AA 21-185)

Catalog No. ABIN566020

This Mouse Monoclonal antibody specifically detects Gastrokine 1 in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 5+ publications.

Quick Overview for Gastrokine 1 antibody (AA 21-185) (ABIN566020)

Target: Gastrokine 1 (GKN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Gastrokine 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2E5

Product Details anti-Gastrokine 1 Antibody

Binding Specificity: AA 21-185

Purpose: Mouse monoclonal antibody raised against a full length recombinant GKN1.

Sequence: NYNINVNDDN NNAGSGQQSV SVNNEHNVAN VDNNNGWDSW NSIWDYGNGF AATRLFQKKT CIVHKMNKEV MPSIQSLDAL VKEKKLQGKG PGGPPPKGLM YSVNPNKVDD LSKFGKNIAN MCRGIPTYMA EEMQEASLFF YSGTCYTTSV LWIVDISFCG DTVEN

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GKN1 (AAH59778, 21 a.a. ~ 185 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Gastrokine 1 antibody (ABIN566020)

Villano, Di Stadio, Federico, Altieri, Miselli, De Palma, Rippa, Arcari: "Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer." in: Journal of negative results in biomedicine, Vol. 15, Issue 1, pp. 14, (2016) (PubMed).

Altieri, Di Stadio, Severino, Sandomenico, Minopoli, Miselli, Di Maro, Ruvo, Chambery, Quagliariello, Masullo, Rippa, Arcari: "Anti-amyloidogenic property of human gastrokine 1." in: Biochimie, Vol. 106, pp. 91-100, (2014) (PubMed).

Mao, Chen, Peng, Yin, Chen, Chen: "Downregulation of gastrokine-1 in gastric cancer tissues and restoration of its expression induced gastric cancer cells to apoptosis." in: Journal of experimental & clinical cancer research : CR, Vol. 31, pp. 49, (2012) (PubMed).

Mao, Chen, Peng, Yin, Chen, Chen: "Helicobacter pylori infection and administration of non-steroidal anti-inflammatory drugs down-regulate the expression of gastrokine-1 in gastric mucosa." in: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, Vol. 23, Issue 3, pp. 212-9, (2012) (PubMed).

Kam, Hennessy, Chua, Gan, Philp, Hon, Lai, Chan, Ong, Wong, Lim, Ling, Tan, Tan, Ho, Kon: "Characterization of the human gastric fluid proteome reveals distinct pH-dependent protein profiles: implications for biomarker studies." in: Journal of proteome research, Vol. 10, Issue 10, pp. 4535-46, (2011) (PubMed).

Target Details for Gastrokine 1

Target: Gastrokine 1 (GKN1)

Alternative Name: GKN1

Background: Full Gene Name: gastrokine 1
Synonyms: AMP18,BRICD1,CA11,FOV,MGC70354,foveolin

Gene ID: 56287