SPIRE1 antibody (AA 482-583)

Catalog No. ABIN566050

This Mouse Monoclonal antibody specifically detects SPIRE1 in ELISA and WB. It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for SPIRE1 antibody (AA 482-583) (ABIN566050)

Target: SPIRE1 (Spire Homolog 1 (Drosophila) (SPIRE1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPIRE1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: 4C5

Product Details anti-SPIRE1 Antibody

Binding Specificity: AA 482-583

Purpose: Mouse monoclonal antibody raised against a partial recombinant SPIRE1.

Sequence: SEKPSTAHHR PLRSIARFSS KSKSMDKSDE ELQFPKELME DWSTMEVCVD CKKFISEIIS SSRRSLVLAN KRARLKRKTQ SFYMSSPGPS EYCPSERTIS EI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SPIRE1 (NP_064533, 482 a.a. ~ 583 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SPIRE1 antibody (ABIN566050)

Morel, Parton, Gruenberg: "Annexin A2-dependent polymerization of actin mediates endosome biogenesis." in: Developmental cell, Vol. 16, Issue 3, pp. 445-57, (2009) (PubMed).

Thom, Bhopale, Mancini, Milovanova: "Actin S-nitrosylation inhibits neutrophil beta2 integrin function." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10822-34, (2008) (PubMed).

Target Details for SPIRE1

Target: SPIRE1 (Spire Homolog 1 (Drosophila) (SPIRE1))

Alternative Name: SPIRE1

Background: Full Gene Name: spire homolog 1 (Drosophila)
Synonyms: MGC150621,MGC150622,Spir-1

Gene ID: 56907

NCBI Accession: NM_020148