DUSP22 antibody (AA 112-184)

Catalog No. ABIN566057

There are 2+ publications for this product available. The Mouse Monoclonal anti-DUSP22 antibody is suitable to detect DUSP22 in samples from Human. It has been validated for WB, ELISA and RNAi.

Quick Overview for DUSP22 antibody (AA 112-184) (ABIN566057)

Target: DUSP22 (Dual Specificity Phosphatase 22 (DUSP22))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DUSP22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, RNA Interference (RNAi)

Clone: 3D3

Product Details anti-DUSP22 Antibody

Binding Specificity: AA 112-184

Purpose: Mouse monoclonal antibody raised against a partial recombinant DUSP22.

Sequence: EDALHTVRAG RSCANPNVGF QRQLQEFEKH EVHQYRQWLK EEYGESPLQD AEEAKNILAA PGILKFWAFL RRL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DUSP22 (NP_064570, 112 a.a. ~ 184 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-DUSP22 antibody (ABIN566057)

Sanchez-Mut, Aso, Heyn, Matsuda, Bock, Ferrer, Esteller: "Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease." in: Hippocampus, Vol. 24, Issue 4, pp. 363-8, (2014) (PubMed).

Li, Fu, Chen, Tan: "JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5472-8, (2010) (PubMed).

Target Details for DUSP22

Target: DUSP22 (Dual Specificity Phosphatase 22 (DUSP22))

Alternative Name: DUSP22

Background: Full Gene Name: dual specificity phosphatase 22
Synonyms: JKAP,JSP1,MKPX,VHX

Gene ID: 56940

NCBI Accession: NM_020185