Sestrin 2 antibody (AA 1-480)

Catalog No. ABIN566510

Product Details anti-Sestrin 2 Antibody

Target: Sestrin 2 (SESN2)

Binding Specificity: AA 1-480

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Sestrin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a full length recombinant SESN2.

Sequence: MIVADSECRA ELKDYLRFAP GGVGDSGPGE EQRESRARRG PRGPSAFIPV EEVLREGAES LEQHLGLEAL MSSGRVDNLA VVMGLHPDYF TSFWRLHYLL LHTDGPLASS WRHYIAIMAA ARHQCSYLVG SHMAEFLQTG GDPEWLLGLH RAPEKLRKLS EINKLLAHRP WLITKEHIQA LLKTGEHTWS LAELIQALVL LTHCHSLSSF VFGCGILPEG DADGSPAPQA PTPPSEQSSP PSRDPLNNSG GFESARDVEA LMERMQQLQE SLLRDEGTSQ EEMESRFELE KSESLLVTPS ADILEPSPHP DMLCFVEDPT FGYEDFTRRG AQAPPTFRAQ DYTWEDHGYS LIQRLYPEGG QLLDEKFQAA YSLTYNTIAM HSGVDTSVLR RAIWNYIHCV FGIRYDDYDY GEVNQLLERN LKVYIKTVAC YPEKTTRRMY NLFWRHFRHS EKVHVNLLLL EARMQAALLY ALRAITRYMT

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SESN2 (AAH13304.1, 1 a.a. ~ 480 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3B8

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Sestrin 2 antibody (ABIN566510)

Li, Sun, Wu, Chen, Deng, Jiang, Feng, Pan, Zhang, Zeng, Zhu: "The inhibition of autophagy sensitises colon cancer cells with wild-type p53 but not mutant p53 to topotecan treatment." in: PLoS ONE, Vol. 7, Issue 9, pp. e45058, (2012) (PubMed).

Liu, Lee, Lee: "Association of platelet-derived growth factor receptor ? accumulation with increased oxidative stress and cellular injury in sestrin 2 silenced human glioblastoma cells." in: FEBS letters, Vol. 585, Issue 12, pp. 1853-8, (2011) (PubMed).

Target Details for Sestrin 2

Target: Sestrin 2 (SESN2)

Alternative Name: SESN2 (SESN2 Products)

Background: Full Gene Name: sestrin 2
Synonyms: DKFZp761M0212,DKFZp761M02121,HI95,SES2,SEST2

Gene ID: 83667