Recombinant CD35 antibody

Catalog No. ABIN5668014

This Rat Monoclonal antibody specifically detects CD35 in FACS, WB, IP and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for Recombinant CD35 antibody (ABIN5668014)

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD35 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 8C12

Product Details anti-CD35 Antibody

Purpose: Anti-CD35 (complement receptor 1) [8C12], Rat IgG2a, kappa

Specificity: Recognises an epitope on CD35 (CR1, 190 kDa), but not on CD21 (CR2, 145-150 kDa), which are alternative splice variants of primary Cr2 gene transcripts.

Characteristics:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: Purified murine CR1 protein.

Isotype: IgG2a kappa

Application Details

Application Notes: This antibody recognises murine CD35, expressed on the majority of peripheral B-cells and peritoneal macrophages and upon fMet-Leu-Phe stimulation also on

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD35

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Alternative Name: CD35 (complement receptor 1)

Background: CR1 , C3BR, C4BR, CD35, KN

UniProt: P17927

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity