Recombinant ITGAL (Efalizumab Biosimilar) antibody
Reactivity: Human
FACS, BR
Host: Rabbit
Monoclonal
hu1124
unconjugated
Recombinant Antibody
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- Target See all ITGAL (Efalizumab Biosimilar) products
- ITGAL (Efalizumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This ITGAL (Efalizumab Biosimilar) antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Blocking Reagent (BR)
- Specificity
- Binds to human LFA-1.
- Characteristics
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OriginalSpeciesName: Human
OriginalFormat: IgG1
- Purification
- Purified antibody.
- Purity
- > 98 % as determined by SDS-PAGE
- Endotoxin Level
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogen
- Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
- Clone
- Hu1124
- Isotype
- IgG kappa
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anti-ITGAL (Efalizumab Biosimilar) antibody
Reactivity: Human FACS, BR Host: Human Monoclonal hu1124 unconjugated Recombinant Antibody
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- Application Notes
- Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.
- Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- ITGAL (Efalizumab Biosimilar)
- Abstract
- ITGAL (Efalizumab Biosimilar) Products
- Synonyms
- CD11A antibody, LFA-1 antibody, LFA1A antibody, integrin subunit alpha L antibody, ITGAL antibody
- Target Type
- Biosimilar
- Background
- LFA-1, integrin alpha L
- UniProt
- P20701
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