Recombinant IL2RA (Daclizumab Biosimilar) antibody
Quick Overview for Recombinant IL2RA (Daclizumab Biosimilar) antibody (ABIN5668118)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Purpose
- Anti-IL-2R [Daclizumab], Human IgG1, kappa
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Specificity
- Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
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Cross-Reactivity
- Cynomolgus, Rhesus Monkey
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Characteristics
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Original Species of Ab: Human
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Purity
- > 98 % as determined by SDS-PAGE
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Endotoxin Level
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
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Immunogen
- Cultured T-cells derived from a patient with Mycosis fungoides.
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Isotype
- IgG1 kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- IL2RA (Daclizumab Biosimilar)
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Target Type
- Biosimilar
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Background
- CD25, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55
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UniProt
- P01589
Target
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