Recombinant IL2RA (Daclizumab Biosimilar) antibody
Quick Overview for Recombinant IL2RA (Daclizumab Biosimilar) antibody (ABIN7487796)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
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Expression System
- Mammalian cells
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Purpose
- Daclizumab Biosimilar - Anti-IL2RA mAb
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Characteristics
- Antibody Type: IgG1-kappa
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Purification
- Recombinant antibody expressed in mammalien cells and purified.
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Isotype
- IgG1 kappa
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Restrictions
- For Research Use only
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Buffer
- PBS pH 7.5
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Storage
- -80 °C
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Storage Comment
- store at -80°C
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- IL2RA (Daclizumab Biosimilar)
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Target Type
- Biosimilar
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Background
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BIIB019,DAC HYP
Daclizumab is a humanized IgG1 monoclonal antibody that binds to human interleukin 2 receptor (anti-Tac or anti-CD25)and composed of human >90%) and murine (10%) antibody sequences. The human sequence is derived from the constant domain of human IgG1 and the variable framework region of Eu myeloma antibody. The murine part was taken from the complementarity-determining regions of a murine anti-Tac antibody. Daclizumab has been used for preventing acute organ rejection in de novo allogeneic kidney transplantation when used simultaneously with immunosuppressive regimens such as cyclosporine and corticosteroid and in the treatment of adult patients with relapsing multiple sclerosis. These trademarks were Zenapax and Zimbryta, respectively. -
CAS-No
- 152923-56-3
Target
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