Recombinant IL2RA (Daclizumab Biosimilar) antibody
Quick Overview for Recombinant IL2RA (Daclizumab Biosimilar) antibody (ABIN5668119)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Purpose
 - Anti-IL-2R [Daclizumab], Rabbit IgG, kappa
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Specificity
 - Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
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Cross-Reactivity
 - Cynomolgus, Rhesus Monkey
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Characteristics
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Original Species of Ab: Human
Original Format of Ab: IgG1
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Purification
 - Protein A affinity purified
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Purity
 - > 98 % as determined by SDS-PAGE
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Endotoxin Level
 - Endotoxin is < 1.0 EU/mg as determined by the LAL method
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Immunogen
 - Cultured T-cells derived from a patient with Mycosis fungoides.
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Isotype
 - IgG kappa
 
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Application Notes
 - Optimal working dilution should be determined by the investigator.
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Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
 - For Research Use only
 
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Concentration
 - 1 mg/mL
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Buffer
 - PBS with 0.02 % Proclin 300.
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Preservative
 - ProClin
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Precaution of Use
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - 4 °C,-20 °C
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Storage Comment
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- IL2RA (Daclizumab Biosimilar)
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Target Type
 - Biosimilar
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Background
 - CD25, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55
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UniProt
 - P01589
 
Target
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