Recombinant CD33 (Gemtuzumab Biosimilar) antibody

Catalog No. ABIN5668210

Product Details anti-CD33 (Gemtuzumab Biosimilar) Antibody

Target: CD33 (Gemtuzumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This CD33 (Gemtuzumab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificity: Recognises human CD33.

Characteristics:

OriginalSpeciesName: Human

OriginalFormat: IgG4

Purification: Purified antibody.

Purity: > 98 % as determined by SDS-PAGE

Endotoxin Level: Endotoxin is < 1.0 EU/mg as determined by the LAL method

Immunogen: Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.

Clone: HP67-6

Isotype: IgG4 kappa

Application Details

Application Notes: A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD33 (Gemtuzumab Biosimilar)

Target: CD33 (Gemtuzumab Biosimilar)

Abstract: CD33 (Gemtuzumab Biosimilar) Products

Synonyms: SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, CD33 molecule antibody, CD33 antibody

Target Type: Biosimilar

Background: Siglec-3

UniProt: P20138