Recombinant Notch1 antibody

Catalog No. ABIN5668273

This anti-Notch1 antibody is a Rabbit Chimeric antibody detecting Notch1 in ELISA and IHC. Suitable for Human and Mouse.

Quick Overview for Recombinant Notch1 antibody (ABIN5668273)

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Chimeric

Conjugate: This Notch1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: E6

Product Details anti-Notch1 Antibody

Purpose: Anti-Notch 1 [E6], Rabbit IgG, lambda

Specificity: An engineered ScFv fragment antibody that binds to both mouse mNRR1 and human hNRR1 but not NRR2.

Cross-Reactivity: Mouse

Characteristics:

Original Species of Ab: Human

Original Format of Ab: scFv

Purification: Protein A affinity purified

Immunogen: This antibody was selected against a fusion protein consisting of EGF domains 1-12 of murine Notch1 fused to a human Fc domain and binds to the NRR of mouse Notch1.

Isotype: IgG lambda

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original human scFv format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for Notch1

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Alternative Name: Notch 1

Background: Tan1, Notch1, Mis6, N1, lin-12, NOTCH1, TAN1, hN1

Pathways: Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development