SH3RF2 antibody (AA 640-729)

Catalog No. ABIN566882

There are 2+ publications for this product available. The Mouse Monoclonal anti-SH3RF2 antibody is suitable to detect SH3RF2 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for SH3RF2 antibody (AA 640-729) (ABIN566882)

Target: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SH3RF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 4E10

Product Details anti-SH3RF2 Antibody

Binding Specificity: AA 640-729

Purpose: Mouse monoclonal antibody raised against a partial recombinant SH3RF2.

Sequence: VKTVRFQNYS PPPTKHYTSH PTSGKPEQPA TLKASQPEAA SLGPEMTVLF AHRSGCHSGQ QTDLRRKSAL AKATTLVSTA SGTQTVFPSK

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SH3RF2 (NP_660205, 640 a.a. ~ 729 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SH3RF2 antibody (ABIN566882)

Kim, Kang, Park, Kim, Hong, Oh, Sohn, Yang, Jang, Lee, Kim, Yoo, Kim, Yeom, Park: "SH3RF2 functions as an oncogene by mediating PAK4 protein stability." in: Carcinogenesis, Vol. 35, Issue 3, pp. 624-34, (2014) (PubMed).

Wilhelm, Kukekov, Schmit, Biagas, Sproul, Gire, Maes, Xu, Greene: "Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein." in: The Journal of biological chemistry, Vol. 287, Issue 3, pp. 2247-56, (2012) (PubMed).

Target Details for SH3RF2

Target: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Alternative Name: SH3RF2

Background: Full Gene Name: SH3 domain containing ring finger 2
Synonyms: FLJ23654,MGC149788,MGC149789,MGC90410,RNF158

Gene ID: 153769

NCBI Accession: NM_152550